BDBM50327623 5-fluoro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)propoxy)isoindolin-1-one::CHEMBL1258535

SMILES Fc1cc2CNC(=O)c2cc1OCCCN1CCN(CC1)c1cccc2cccc(F)c12

InChI Key InChIKey=XMDALBYMLNOLMP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327623   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327623(5-fluoro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  1.19nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327623(5-fluoro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  9.54nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327623(5-fluoro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  15.6nMAssay Description:Displacement of [3H]-citalopram from human serotonin transporter expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed