BDBM50329764 4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin-4-yl]amino}methyl)benzenesulfonamide::4-{[N-(6-Chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]methyl}benzenesulfonamide::CHEMBL1233735

SMILES CSc1nc(Cl)c(C=O)c(NCc2ccc(cc2)S(N)(=O)=O)n1

InChI Key InChIKey=NPWLBLGDDVPXFE-UHFFFAOYSA-N

Data  8 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50329764   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  7nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  83nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  24nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  130nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  100nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  100nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  28nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329764(4-({[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin...)
Affinity DataKd:  43nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair