BDBM50329798 (Z)-N-ethyl-N-methyl-3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxamide::CHEMBL1269806

SMILES CCN(C)C(=O)c1ccc2C(C(=Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=LOHIFTFZMRATFH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329798   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329798((Z)-N-ethyl-N-methyl-3-((4-(N-methyl-2-(4-methylpi...)
Affinity DataIC50:  7nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329798((Z)-N-ethyl-N-methyl-3-((4-(N-methyl-2-(4-methylpi...)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329798((Z)-N-ethyl-N-methyl-3-((4-(N-methyl-2-(4-methylpi...)
Affinity DataEC50:  833nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed