BDBM50329822 5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chlorobenzenesulfonamide::CHEMBL1272242::N-alkylated benzimidazole derivative, 4d::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 5

SMILES: NS(=O)(=O)c1cc(ccc1Cl)C(=O)Cn1c(Cc2ccccc2)nc2ccccc12

InChI Key: InChIKey=UUAIBIWLOHLXLK-UHFFFAOYSA-N

Data: 23 Kd  8 K_off  4 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50329822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	2.00E+5	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	8.30E+4	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0430	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	3.80E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0610	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.33E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	769	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.33E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0430	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0610	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329822 (5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair