BDBM50329836 2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfanyl)acetyl]benzenesulfonamide::CHEMBL1271639

SMILES NS(=O)(=O)c1cc(ccc1Cl)C(=O)CSc1nc2c(cnc3ccccc23)[nH]1

InChI Key InChIKey=APUFNRAMLCSAKF-UHFFFAOYSA-N

Data  3 KI  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50329836   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50329836(2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfany...)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition constant incubated for 10 mins by phenol red dye based stopped-flow CO2 h...More data for this Ligand-Target Pair
In DepthDetails PubMedMMDB

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50329836(2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfany...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 assessed as inhibition constant incubated for 10 mins by phenol red dye based stopped-flow CO2 ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50329836(2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfany...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 assessed as inhibition constant incubated for 10 mins by phenol red dye based stopped-flow CO2 h...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329836(2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfany...)
Affinity DataKd:  100nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50329836(2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfany...)
Affinity DataKd:  30nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50329836(2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfany...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329836(2-Chloro-5-[(1H-imidazo[4,5-c]quinolin-2-ylsulfany...)
Affinity DataKd:  100nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed