BDBM50329857 2-phenyl-1H-imidazole-4-carboxylic acid::CHEMBL1232889::US9487462, 40

SMILES OC(=O)c1cnc([nH]1)-c1ccccc1

InChI Key InChIKey=XCAXKZJNJCKTQH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329857   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmahungary 2000

US Patent
LigandPNGBDBM50329857(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Affinity DataIC50:  1.37E+5nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50329857(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmahungary 2000

US Patent
LigandPNGBDBM50329857(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Affinity DataIC50:  1.65E+5nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmahungary 2000

US Patent
LigandPNGBDBM50329857(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Affinity DataIC50:  2.50E+5nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In DepthDetails US Patent