BDBM503317 6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(2,3-dichloro- phenyl)-pyrimidine-4-carboxylic- acid-(2-hydroxy-ethyl)-amide::US11033547, Compound 17::US11696916, Compound 17
SMILES CC1(N)CCN(CC1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(=O)NCCO
InChI Key InChIKey=IWMGAWPGQYIEED-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503317
Affinity DataIC50: 1.20E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair