BDBM503335 2-((R)-6-Amino-2-aza- spiro[4.4]non-2-yl)-5-(2,3-dichloro- phenyl)-6-methyl-pyrimidine-4- carboxylic acid amide::US11033547, Compound 35::US11696916, Compound 35
SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1CCC2(CCC[C@H]2N)C1
InChI Key InChIKey=AZIVYVCMTYVJJH-QMRFKDRMSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503335
Affinity DataIC50: 1.10E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair