BDBM50333999 CHEMBL1644629::N-(4-(4-(naphthalen-2-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyridin-2-yl)acetamide

SMILES CC(=O)Nc1cc(ccn1)-c1n[nH]c(=O)n1-c1ccc2ccccc2c1

InChI Key InChIKey=HCFNWGLCDCAOAC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50333999   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333999(CHEMBL1644629 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333999(CHEMBL1644629 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333999(CHEMBL1644629 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333999(CHEMBL1644629 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant ERK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333999(CHEMBL1644629 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed