BDBM50335566 CHEMBL1651026::Substance P [Sar9,Met(O2)11]
SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]S([#6])(=O)=O)-[#6](-[#7])=O
InChI Key InChIKey=OUPXSLGGCPUZJJ-SARDKLJWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50335566
Affinity DataKi: 0.140nMAssay Description:Binding affinity to human NK1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human U373MG cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Binding affinity to human NK1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human U373MG cells measured after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Binding affinity to human NK1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human tachykinin NK1 receptorMore data for this Ligand-Target Pair