BDBM503358 2-(1-Amino-5-aza-spiro[2.4]hept-5- yl)-5-(2,3-dichloro-phenyl)-6- methyl-pyrimidine-4-carboxylic acid amide::US11033547, Compound 58::US11696916, Compound 58
SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1CCC2(CC2N)C1
InChI Key InChIKey=UZBGMFWCZBXQJJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503358
Affinity DataIC50: 4.40E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair