BDBM503361 6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(7-chloro-1H- indazol-6-yl)-pyrimidine-4- carboxylic acid amide::US11033547, Compound 62::US11696916, Compound 62

SMILES CC1(N)CCN(CC1)c1nc(N)c(-c2ccc3cn[nH]c3c2Cl)c(n1)C(N)=O

InChI Key InChIKey=XKHYPRKOQBFHHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503361   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM503361(6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(7-...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503361(6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(7-...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent