BDBM50336319 CHEMBL1667937::trans-4-(8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)cyclohexanecarboxylic acid

SMILES Nc1nccn2c(nc(-c3ccc4ccc(nc4c3F)-c3ccccc3)c12)[C@H]1CC[C@@H](CC1)C(O)=O

InChI Key InChIKey=NEGAWQQFSSYDOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336319   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336319(trans-4-(8-amino-1-(8-fluoro-2-phenylquinolin-7-yl...)
Affinity DataIC50: 285nMAssay Description:Inhibition of human IGF1R expressed in mouse 3T3 cells by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed