BDBM50336871 CHEMBL1672319::N-(2-morpholino-6-(pyrazin-2-yl)pyrimidin-4-yl)quinolin-3-amine

SMILES C1CN(CCO1)c1nc(Nc2cnc3ccccc3c2)cc(n1)-c1cnccn1

InChI Key InChIKey=RPVDBMPBQDMVTR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336871   

LigandPNGBDBM50336871(CHEMBL1672319 | N-(2-morpholino-6-(pyrazin-2-yl)py...)
Affinity DataEC50:  390nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser473 in human A2780 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50336871(CHEMBL1672319 | N-(2-morpholino-6-(pyrazin-2-yl)py...)
Affinity DataIC50:  231nMAssay Description:Inhibition of PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed