BDBM50338976 2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chromen-4-one::2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one::5,6,7,8,3',4'-hexamethoxyflavone::CHEMBL76447::NSC-76751::nobiletin

SMILES COc1ccc(cc1OC)-c1cc(=O)c2c(OC)c(OC)c(OC)c(OC)c2o1

InChI Key InChIKey=MRIAQLRQZPPODS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50338976   

LigandPNGBDBM50338976(2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chro...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50338976(2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50338976(2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chro...)
Affinity DataIC50:  1.15E+4nMAssay Description:TP_TRANSPORTER: inhibition of Daunorubicin efflux in NIH-3T3-G185 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50338976(2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chro...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed