BDBM50339006 6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine::6-(2-aminopyrimidin-4-yl)-1H-indazol-3-amine::CHEMBL1688215

SMILES: Nc1n[nH]c2cc(ccc12)-c1ccnc(N)n1

InChI Key: InChIKey=QVWIVWPIJUYRRF-UHFFFAOYSA-N

Data: 22 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50339006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 5 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase beta-1 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50339006 (6-(2-Amino-4-pyrimidinyl)-1H-indazol-3-amine | 6-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
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