BDBM50340954 CHEMBL1762110::Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl)cyclohexyl)methyl)acetamide

SMILES: CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12

InChI Key: InChIKey=MKMYAVUUMSCFQQ-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50340954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50340954 (Trans-N-((-4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
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