BDBM50342167 CHEMBL1766169::rac-1-[1,1'-biphenyl]-3-yl-1-(1H-imidazol-4-yl)-2-methyl-1-propanol

SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=MSYJBDGOMUPKGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342167   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342167(CHEMBL1766169 | rac-1-[1,1'-biphenyl]-3-yl-1-(1H-i...)
Affinity DataIC50:  15nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342167(CHEMBL1766169 | rac-1-[1,1'-biphenyl]-3-yl-1-(1H-i...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342167(CHEMBL1766169 | rac-1-[1,1'-biphenyl]-3-yl-1-(1H-i...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human 17,20 lyase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed