BDBM50342911 5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6-yl)furan-2-carboxylic acid::CHEMBL1724489

SMILES Cc1ccc(CNc2ncnc3ccc(cc23)-c2ccc(o2)C(O)=O)o1

InChI Key InChIKey=YEJQKCNMELQRPL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342911   

TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342911(5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...)
Affinity DataIC50: 104nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342911(5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342911(5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342911(5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342911(5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342911(5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed