BDBM50343384 4-(2-(2-(1H-pyrazol-1-yl)ethoxy)-4,6-dichlorophenyl)-2-amino-N-cyclopropyl-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxamide::CHEMBL1774922

SMILES Nc1nc2CN(Cc2c(n1)-c1c(Cl)cc(Cl)cc1OCCn1cccn1)C(=O)NC1CC1

InChI Key InChIKey=PLTNGPNDMXCAGM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343384   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343384(4-(2-(2-(1H-pyrazol-1-yl)ethoxy)-4,6-dichloropheny...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed