BDBM50344164 (R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutanecarboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1778524

SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)C(=O)C1(CCC1)c1ccc(F)cc1

InChI Key InChIKey=QYRBBRRASAPCLC-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50344164   

TargetProstaglandin D2 receptor 2(Human)
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344164((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutaneca...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human CRTH2 receptor expressed in HEK293-EBNA cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344164((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutaneca...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK293-EBNA cells assessed as inhibition of forskolin-stimulated intracellular cAMP producti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344164((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutaneca...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344164((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutaneca...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed