BDBM50344792 5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylphenyl)furan-2-carboxamide::CHEMBL1779895

SMILES Cc1cc(O)cc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl

InChI Key InChIKey=JEYPFNBXIDDNSZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50344792   

TargetSphingosine 1-phosphate receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344792(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344792(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of S1P2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344792(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of S1P5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344792(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of S1P1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344792(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of S1P3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed