BDBM50344821 10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diazatetracyclo[7.3.1.13,11.03,8]tetradecane-1,2,7,10,14-pentaol::10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diazatetracyclo[7.3.1.13,11.03,8]tetradecane-1,2,7,10,14-pentaolCitrate::CHEMBL507974::tetrodotoxin

SMILES: C([C@@]1([C@H]2[C@@H]3[C@H](N=C(N[C@@]34[C@@H]([C@@H]1O[C@]([C@H]4O)(O2)O)O)N)O)O)O

InChI Key: InChIKey=CFMYXEVWODSLAX-UHFFFAOYSA-N

Data: 23 IC50  1 Kd

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50344821   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 10 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 9 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 4 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 1 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 11 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 3 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 8 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 2 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 2 subunit alpha (Rat)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rat)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 11 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 3 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 3 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 1/2/3/4/5/8/9/10/11 subunit alpha (Rat)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 8 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 4 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 7 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 10 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 3 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 1 subunit alpha (Human)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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