BDBM50346952 CHEMBL1795712::CHEMBL1795715

SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)c1cccc(I)c1

InChI Key InChIKey=OWOWCHRXILVEKL-HJUABUFYSA-N

Data  6 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50346952   

TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]-U69593 from KOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKi:  0.220nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned MOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-DAMGO from MOR-1 expressed in CHO cells after 150 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKi:  2.55nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned DOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-DPDPE from DOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKd:  0.0500nMAssay Description:Binding affinity to KOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to DOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795712 | CHEMBL1795715)
Affinity DataKd:  0.220nMAssay Description:Binding affinity to MOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed