BDBM50349344 CHEMBL1809250

SMILES CCC(NCc1ccc(C(=N)N)cc1)C(=O)[C@@H](CCCN=C(N)N)NS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=DBLNNDOSJLJNTF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50349344   

TargetCoagulation factor X(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349344BDBM50349344(CHEMBL1809250)
Affinity DataKi:  2.10nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTransmembrane protease serine 11D(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349344BDBM50349344(CHEMBL1809250)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349344BDBM50349344(CHEMBL1809250)
Affinity DataKi:  29nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTransmembrane protease serine 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349344BDBM50349344(CHEMBL1809250)
Affinity DataKi:  53nMAssay Description:Inhibition of recombinant catalytic domain of TMPRSS2 expressed in Escherichia coli using Dcyclohexylalanine- Pro-Arg-AMC as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349344BDBM50349344(CHEMBL1809250)
Affinity DataKi:  3.03E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed