BDBM50350394 CHEMBL528045
SMILES CC(=O)NC(c1cccs1)c1cc(Cl)c2cccnc2c1O
InChI Key InChIKey=UZLBHGBBHNHZNS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50350394
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Competitive inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as 12-HPETE formation using arachidonic acid by by Mi...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 5-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human reticulocyte N-terminally His6-tagged 15-lipoxygenase-1 assessed as conjugated diene product formation using arachidonic acid by ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by U...More data for this Ligand-Target Pair