BDBM50352737 CHEMBL1823064

SMILES Cc1c(nc(-c2ccccc2)n1-c1ccccc1)C(=O)NCCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=GSOKOLQABSVSMM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352737   

TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352737(CHEMBL1823064)
Affinity DataIC50: 20.5nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352737(CHEMBL1823064)
Affinity DataIC50: 29.4nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352737(CHEMBL1823064)
Affinity DataIC50: 193nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed