BDBM50353844 CHEMBL270341::US9604926, Compound CM-145::US9724435, Compound CM-145
SMILES O=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
InChI Key InChIKey=ZACKDLLCPUTVQK-UHFFFAOYSA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50353844
Affinity DataKi: 0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University of Mississippi
US Patent
The University of Mississippi
US Patent
Affinity DataKi: 4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University of Mississippi
US Patent
The University of Mississippi
US Patent
Affinity DataKi: 4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 4.17nMAssay Description:Displacement of [3H](+)-pentazocine from opioid sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 4.17nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat brain membrane after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair