BDBM50355467 CHEMBL1833992
SMILES COc1ccc(cc1Nc1nc(N)n(n1)-c1ccccn1)N1CCOCC1
InChI Key InChIKey=WPFRNEQAKJNVPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50355467
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of IRAK4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of Aurora A by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of JAK2 by spectrophotometryMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair