BDBM50357721 CHEMBL1915978

SMILES CCC[C@@H](O)[C@H]1CCN([C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)CNCc2cccc(OC)c2)C1=O

InChI Key InChIKey=ZRBJRIFNTXBCRI-BWNLSPMZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357721   

TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357721(CHEMBL1915978)
Affinity DataIC50:  90nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing swedish mutant APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357721(CHEMBL1915978)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of BACE1 by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed