BDBM50362895 Lactoflavin::RIBOFLAVIN

SMILES Cc1cc2nc3c(nc(=O)[nH]c3=O)n(C[C@H](O)[C@H](O)[C@H](O)CO)c2cc1C

InChI Key InChIKey=AUNGANRZJHBGPY-SCRDCRAPSA-N

Data  1 KI  5 IC50  4 Kd

PDB links: 70 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50362895   

TargetRiboflavin-binding protein(Chicken)
Calvin College

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataKi:  350nMAssay Description:Competitive inhibition of chicken riboflavin binding protein by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRiboflavin-binding protein(Chicken)
Calvin College

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataKd:  6.60nMpH: 7.4Assay Description:Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 7.4 in 0.1 M phosphate buffer by isothermal titration ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRiboflavin-binding protein(Chicken)
Calvin College

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataKd:  46nMpH: 4.0Assay Description:Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 4 in 0.1 M NaAc by isothermal titration calorimetric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRiboflavin-binding protein(Chicken)
Calvin College

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataKd:  34nMpH: 9.0Assay Description:Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 9 in 0.1 M Tris by isothermal titration calorimetric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target60 kDa heat shock protein, mitochondrial(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRiboflavin-binding protein(Chicken)
Calvin College

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataKd:  5nMpH: 7.4Assay Description:Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 7.4 in phosphate buffer by isothermal titration calori...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThiosulfate sulfurtransferase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChaperonin GroEL(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50362895(Lactoflavin | RIBOFLAVIN)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed