BDBM50366654 CHEMBL4168620

SMILES N[C@H]([C@H](OCC#N)C(O)=O)C(O)=O

InChI Key InChIKey=GJJKATZBLBTZJD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50366654   

TargetExcitatory amino acid transporter 3(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 8.13E+4nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 4(Rat)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 4(Rat)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366654BDBM50366654(CHEMBL4168620)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed