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BDBM50368145 CHEMBL1788212

SMILES: Oc1cccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c12

InChI Key: InChIKey=AUVXRDCLWMODQH-MRXNPFEDSA-N

Data: 3 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368145   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50368145
PNG
(CHEMBL1788212)
Show SMILES Oc1cccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c12
Show InChI InChI=1S/C19H19NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h2-8,16,21H,1,9-12H2/t16-/m1/s1
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Similars

Article
PubMed
2n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to inhibit dopamine receptor D2 in rat striatum using [3H]-spiperone


J Med Chem 34: 24-8 (1991)


Article DOI: 10.1021/jm00105a005
BindingDB Entry DOI: 10.7270/Q24Q7VKQ
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50368145
PNG
(CHEMBL1788212)
Show SMILES Oc1cccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c12
Show InChI InChI=1S/C19H19NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h2-8,16,21H,1,9-12H2/t16-/m1/s1
MMDB

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Article
PubMed
0.0340n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to inhibit Striatal Dopamine Receptor in rat brain through radioreceptor assay carried out with agonist ligand...


J Med Chem 34: 24-8 (1991)


Article DOI: 10.1021/jm00105a005
BindingDB Entry DOI: 10.7270/Q24Q7VKQ
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50368145
PNG
(CHEMBL1788212)
Show SMILES Oc1cccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c12
Show InChI InChI=1S/C19H19NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h2-8,16,21H,1,9-12H2/t16-/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
452n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to inhibit dopamine receptor D1 in rat striatum using [3H]SCH-23390


J Med Chem 34: 24-8 (1991)


Article DOI: 10.1021/jm00105a005
BindingDB Entry DOI: 10.7270/Q24Q7VKQ
More data for this
Ligand-Target Pair