BDBM50368992 CHEMBL4170027

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(cs2)-c2ccc(cc2Cl)C#N)cc1

InChI Key InChIKey=ROHQEOBEESTMOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50368992   

TargetNuclear receptor ROR-gamma(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50368992(CHEMBL4170027)
Affinity DataIC50: 780nMAssay Description:Inverse agonist activity at biotinylated HN-Avi-MBP-TCS-human RORgammat (258 to 518 residues) assessed as inhibition of biotinylated SRC-1 peptide NC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50368992(CHEMBL4170027)
Affinity DataIC50: 1.16E+3nMAssay Description:Displacement of [3H]-2-(4-(ethylsulfonyl)phenyl)-N-(4-(2-(methoxymethyl)phenyl)thiophen-2-yl)acetamide from purified N-(HN)6-GST-TCS-human RORgammat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed