BDBM50369323 MECAMYLAMINE
SMILES CN[C@]1(C)[C@@H]2CC[C@@H](C2)C1(C)C
InChI Key InChIKey=IMYZQPCYWPFTAG-IQJOONFLSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50369323
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
The Ohio State University
Curated by ChEMBL
The Ohio State University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK-tsA201 cells assessed as inhibition of epibatidine-induced intracellular calcium leve...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Ohio University
Curated by ChEMBL
Ohio University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against nicotinic acetylcholine receptor alpha3-beta4More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at human alpha7 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha2/beta4(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha2-beta4More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha2/beta4(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha2-beta4More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Ability to block activation of acetylcholine-stimulated currents in human alpha-7 homomers expressed in oocytesMore data for this Ligand-Target Pair