BDBM50375219 CHEMBL258939

SMILES [#6]\[#6](-[#6])=[#6]\[#6](-[#8])-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1c2ccoc2cc2oc(=O)ccc12

InChI Key InChIKey=QJNWCPZVQVDFFW-UHFFFAOYSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50375219   

TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataKi:  1.42E+3nMAssay Description:Displacement of [3H]SCH-23390 from rat HA-tagged D1 dopamine receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from mouse delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human BACE1 using fluorogenic polypeptide Mca-SEVNLDAEFRK(Dpn)RRNH2 as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed