BDBM50379224 CHEMBL2011297::US9416123, 11
SMILES Nc1c(c(nn1-c1ccc(cc1)C#N)-c1ccncc1)-c1ccc(F)cc1
InChI Key InChIKey=ANRRTHFTTBOMDY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50379224
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair