BDBM50380148 CHEMBL2011156::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 6

SMILES: c1cnc(nc1)SCC(=O)c2ccc(cc2)S(=O)(=O)N

InChI Key: InChIKey=GQFCFNQXNFZIFC-UHFFFAOYSA-N

Data: 44 Kd  18 K_off  12 K_on

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 74 hits for monomerid = 50380148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 13 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	260	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.160	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	6.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	6.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.25	n/a	6.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	6.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	6.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.290	n/a	6.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0170	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0120	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	38	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.210	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	140	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	90	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.120	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0220	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.30E+6	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00800	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.120	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	80	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	62	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.140	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0220	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	556	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Rhesus macaque)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0120	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0170	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.210	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380148 (CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair