BDBM50384372 CHEMBL2031466

SMILES CC(C)NC(=O)c1ccc(C)c(c1)-n1cnc2ccc(cc2c1=O)N1CCN(C)CC1

InChI Key InChIKey=HEQNUTDAQBNSDS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50384372   

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384372(CHEMBL2031466)
Affinity DataIC50: 155nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384372(CHEMBL2031466)
Affinity DataIC50: 156nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384372(CHEMBL2031466)
Affinity DataIC50: 794nMAssay Description:Inhibition of p38alpha-mediated TNFalpha secretion in LPS-stimulated human whole blood assessed as IC50 equals to free drug concentration at human wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384372(CHEMBL2031466)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of p38alpha-mediated TNFalpha secretion in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384372(CHEMBL2031466)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of p38alpha-mediated TNFalpha secretion in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed