BDBM50387320 CHEMBL2046609

SMILES COc1ccc(\C=C\C(=O)Nc2ccc(cc2)C(=O)N2CCc3nc(sc3C2)C(=O)NO)cc1

InChI Key InChIKey=MUFLGCDHPGLRNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50387320   

TargetHistone deacetylase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50387320(CHEMBL2046609)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant His6-tagged and GST-fuses HDAC6 expressed in insect High5 cells using Boc-Lys(eacetyl)- AMC as substrate after 3 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50387320(CHEMBL2046609)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of human recombinant His6-tagged and GST-fuses HDAC3 expressed in insect High5 cells using Ac-Lys-Tyr-Lys(e-acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50387320(CHEMBL2046609)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human recombinant His6-tagged and GST-fuses HDAC1 expressed in insect High5 cells using Ac-Lys-Tyr-Lys(e-acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed