BDBM50391197 CHEMBL2088675

SMILES COc1ccc2n(Cc3cccc(c3)C#N)c3c(c(C)n[nH]c3=O)c2c1

InChI Key InChIKey=KJDFVVUZTRUIIC-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391197   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

LigandBDBM50391197(CHEMBL2088675)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50391197(CHEMBL2088675)Copy SMILESCopy InChI

Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50391197(CHEMBL2088675)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI