BDBM50393255 CHEMBL2151572

SMILES Clc1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2

InChI Key InChIKey=SSRDSYXGYPJKRR-ZDUSSCGKSA-N

Data  2 KI  1 IC50  3 EC50

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50393255   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataKi:  4.30nMAssay Description:Binding affinity to human alpha7 nAchRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataKi:  9.98nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataEC50:  390nMAssay Description:Partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes by voltage clamp electrophysiological methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataIC50:  299nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataEC50:  340nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in xenopus oocytesMore data for this Ligand-Target Pair