BDBM50396147 CHEMBL2171746::US8802674, 314
SMILES CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)ncc1C#N
InChI Key InChIKey=LYEWAGXEEPXHOF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50396147
Affinity DataKi: 2.40nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of LRRK2 using FAM-LRRKtide as substrate after 120 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
Affinity DataKi: >3.20E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of autophosphorylation of LRRK2 in human HEK293 cellsMore data for this Ligand-Target Pair