BDBM50396704 CHEMBL2172072

SMILES CNC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccccc2C1

InChI Key InChIKey=PBBCJGRZQLBCCD-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50396704   

TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50396704(CHEMBL2172072)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C4 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50396704(CHEMBL2172072)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C2 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50396704(CHEMBL2172072)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C1 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50396704(CHEMBL2172072)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant His-tagged AKR1C3 expressed in Escherichia coli BL21 (DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-az...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50396704(CHEMBL2172072)
Affinity DataIC50:  13nMAssay Description:Inhibition of AKR1C3 overexpressed in human HCT116 cells assessed as inhibition of PR-104A conversion to hydroxylamine after 2 hrs by spectrophotomet...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50396704(CHEMBL2172072)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant His-tagged AKR1C3 expressed in Escherichia coli BL21 (DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-az...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50396704(CHEMBL2172072)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair