BDBM50397847 CHEMBL2179097

SMILES C[C@@H]1CNC[C@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1

InChI Key InChIKey=PYXRQSYDODFUOC-MWLCHTKSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397847   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397847(CHEMBL2179097)
Affinity DataIC50:  89nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50397847(CHEMBL2179097)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed