BDBM50398699 CHEMBL214393

SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O

InChI Key InChIKey=DJJCXFVJDGTHFX-XVFCMESISA-N

Data  3 KI  1 IC50  1 Kd

PDB links: 23 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50398699   

TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of human ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetProtein argonaute-2(Homo sapiens)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to human Argonaut protein 2 PAZ domain assessed as dissociation constant by using isothermal titration microcalorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataIC50: >5.00E+6nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed