BDBM50400824 CHEMBL2204342
SMILES COc1ccc(cc1)[C@@H](CN(C)C)[Si]1(O)CCCCC1
InChI Key InChIKey=KIXBFSFRCBHKLN-MRXNPFEDSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50400824
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of human NET expressed in MDCK cells assessed as decrease in [3H]-noradrenaline reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells assessed as decrease in [3H]-dopamine reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL
Affinity DataIC50: 791nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as decrease in [3H]-serotonin reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL