BDBM2274 2-Pyridinone derivative 55::3-[2-(1,3-benzoxazol-2-yl)ethyl]-5-ethyl-1,2-dihydropyridin-2-one::3-[2-(Benzoxazol-2-yl)ethyl]-5-ethylpyridin-2(1H)-one::CHEMBL177191

SMILES CCc1c[nH]c(=O)c(CCc2nc3ccccc3o2)c1

InChI Key InChIKey=GYMVKFBOCODOGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2274   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Reserch Laboratories

Curated by ChEMBL
LigandPNGBDBM2274(3-[2-(Benzoxazol-2-yl)ethyl]-5-ethylpyridin-2(1H)-...)
Affinity DataIC50: 177nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Merck Reserch Laboratories

Curated by ChEMBL
LigandPNGBDBM2274(3-[2-(Benzoxazol-2-yl)ethyl]-5-ethylpyridin-2(1H)-...)
Affinity DataIC50: 177nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed