BDBM50408152 CHEMBL53662

SMILES COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21

InChI Key InChIKey=ACSDLURGGYXLSE-UHFFFAOYSA-N

Data  6 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50408152   

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408152(CHEMBL53662)
Show SMILES COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21
Show InChI InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3
Affinity DataIC50: 6.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408152(CHEMBL53662)
Show SMILES COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21
Show InChI InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408152(CHEMBL53662)
Show SMILES COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21
Show InChI InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3
Affinity DataIC50: 4.17E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408152(CHEMBL53662)
Show SMILES COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21
Show InChI InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3
Affinity DataIC50: 6.92E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408152(CHEMBL53662)
Show SMILES COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21
Show InChI InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]N-methyl-mesulergine as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(BOVINE)
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408152(CHEMBL53662)
Show SMILES COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21
Show InChI InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair