BDBM50413563 CHEMBL469376

SMILES C[C@@H]1CN(CCN1CCCc1cccc2N(C)C(=O)COc12)c1cccc2nc(C)ccc12

InChI Key InChIKey=GIQHYUIXZZZJQF-HXUWFJFHSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50413563   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413563(CHEMBL469376)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]citalopram human SerT receptor expressed in LLCPK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413563(CHEMBL469376)
Affinity DataKi:  0.631nMAssay Description:Antagonist activity at human 5HT1D assessed as GTPgammaS binding by scintillation proximity assay in presence of 5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413563(CHEMBL469376)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human 5HT1A assessed as GTPgammaS binding by scintillation proximity assay in presence of 5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413563(CHEMBL469376)
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of [3H]dofetilide human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413563(CHEMBL469376)
Affinity DataEC50:  25.1nMAssay Description:Agonist activity at human 5HT1B assessed as GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed